Induction of melanogenesis by 4′-O-methylated flavonoids in B16F10 melanoma cells
I Horibe, Y Satoh, Y Shiota, A Kumagai… - Journal of natural …, 2013 - Springer
Agents to control melanogenesis are in demand for the development of cosmetics to
improve pigmentation disorders of skin and hair. In this study, we examined and evaluated
the effects of flavonoids on melanogenesis in the melanogenic cells model, murine B16F10
melanoma cells. In the course of this study, we found that incubation of the cells in a medium
containing 10 μM of the 4′-O-methylated flavonoids, diosmetin (4′-O-methylluteolin),
acacetin (4′-O-methylapigenin) or kaempferide (4′-O-methylkaempferol), increased the …
improve pigmentation disorders of skin and hair. In this study, we examined and evaluated
the effects of flavonoids on melanogenesis in the melanogenic cells model, murine B16F10
melanoma cells. In the course of this study, we found that incubation of the cells in a medium
containing 10 μM of the 4′-O-methylated flavonoids, diosmetin (4′-O-methylluteolin),
acacetin (4′-O-methylapigenin) or kaempferide (4′-O-methylkaempferol), increased the …
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